AMeLie is one of ten projects in a call for proposals by the "Bundesministeriums für Bildung und Forschung" on the topic of mastering the complexity of socio-technical systems. The project, which was launched in 2020, is intended to make a contribution to Advanced Systems Engineering (ASE) for the value creation of tomorrow. AMeLie is thus a pioneer of ASE conceptualization. The meaning of the acronym AMeLie is: "Neue Advanced Systems Engineering-Methoden für Entwicklungsprozesse anhand von Produktbeispielen aus Medizintechnik und Lifesciences", which translates to "New Advanced Systems Engineering methods for development processes based on product examples from medical technology and life sciences".